The best museums in San Luis Obispo in September 2025

These are the top 5 best museums in San Luis Obispo, United States, ranked by their rating and popularity in 2025. Click a museum for more information about the museum, including visitor information, exhibitions and reviews.

For a complete overview of museums in San Luis Obispo, their exhibitions and discount cards & passes, see our overview page with all museums in San Luis Obispo.

Looking for the best museums in San Luis Obispo? These are the best ones:

  1. San Luis Obispo Railroad Museum1

    San Luis Obispo Railroad Museum

     San Luis Obispo, CA
    The San Luis Obispo Railroad Museum is a significant institution dedicated to preserving and showcasing the railroad history of California, particularly the Central Coast. The museum achieves this through the collection, restoration, display, and operation of historic railroad equipment. This offers visitors a unique opportunity to delve into the rich history of California's railroads and understand their impact on the region's development.
  2. San Luis Obispo Botanical Garden2

    San Luis Obispo Botanical Garden

     San Luis Obispo, CA
    The San Luis Obispo Botanical Garden is unique in its collection of plants from the five Mediterranean climate zones. These zones include California, Chile, Australia, South Africa, and the countries of the Mediterranean basin. This diverse collection offers visitors a chance to explore and learn about a wide variety of plant species from around the world.
  3. 3

    San Luis Obispo Children’s Museum

     San Luis Obispo, CA
  4. History Center of San Luis Obispo4

    History Center of San Luis Obispo

     San Luis Obispo, CA
    The San Luis Obispo Carnegie Library is a significant historical site located at 696 Monterey St. in San Luis Obispo, California. This library is a part of the Carnegie library system, which was a philanthropic endeavor by Andrew Carnegie to promote education and literacy. The library's location in the heart of the city makes it easily accessible for tourists.
  5. Jack House and Gardens5

    Jack House and Gardens

     San Luis Obispo, CA
    The Robert Jack House is a historic site located at 536 Marsh St. in San Luis Obispo, California. This two-story house is designed in the Italianate style, a popular architectural style during the 19th century. The house's design and history make it a significant landmark in the city.

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